The RAS-RAF-MEK-ERK signaling pathway (MAPK signaling pathway) plays a significant role in multiple pathological behaviors and is most frequently dysregulated in more than 30% of human cancers. As key elements in this pathway. MEK1/2 play crucial roles in tumorigenesis and the inhibition of apoptosis. which makes their inhibition an attractive antitumor strategy. https://toyscyclers.shop/product-category/activity-equipment/
Synergistic inhibition of MEK and reciprocal feedback networks for targeted intervention in malignancy
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